Bollywood's veteran actors, Amitabh Bachchan and Sharmila Tagore had played husband-wife in 2005 movie, 'Viruddh'. However, in 1984 film, 'Desh Preme', Sharmila played Amitabh's mother's role.
One of the most romantic couples, Aishwarya and Shah Rukh Khan who played as lovers in 'Devdas' and 'Mohabbatein', had once played each other's siblings in 'Josh'.
Waheeda had once played Amitabh's wife's role in 'Kabhie Kabhie'. However, after she had turned 40 years old, she played Amitabh's mother's role in films, 'Trishul', 'Namak Halal' and a few others.
Nargis is known for her role in the film, 'Mother India', where she played Sunil Dutt's mother's character. However, after 6 years of their marriage the duo were casted in 'Yaadein' as husband-wife.
Deepika Padukone and John Abraham played lovers in the movie, 'Desi Boyz'. However, in the film, 'Race 2', the duo had been casted as the notorious brother and sister.
Sridevi and Rajinikanth's iconic onscreen chemistry in the movie, 'Chalbaaz' is still remembered. However, in 1976 Tamil movie, 'Moondru Mudichu', a teenager Sridevi had played his mother's role.
In Deepika's debut movie, 'Om Shanti Om, she and Arjun Rampal had played husband-wife. However, later in the film, 'Housefull', they were casted as loving siblings.
Salman Khan had launched Daisy Shah in his film, 'Jai Ho', where they can be seen playing as lovers. However in 'Race 3', the duo played brother and sister's roles.
Iconic couple, Amitabh and Rakhee had played lovers and husband-wife in many movies, including 'Kabhie Kabhie'. But, in later years, the actress was casted as his mother in a few films like 'Shakti'.
In 'Bajirao Mastani', Priyanka and Ranveer's onscreen chemistry as Kashibai and Bajirao was applauded. However, later in 'Dil Dhadakne Do', she was seen as his sister.