Is Ben Sasse's Wife Melissa Suffering From Brain Aneurysm, Memory Loss And Epilepsy?

Ben Sasse recently announced of being diagnosed with an advanced stage of pancreatic cancer. However, has his wife, Melissa, also been suffering from a major health scare?

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By Siddhi Chatterjee Last Updated:

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Is Ben Sasse's Wife Melissa Suffering From Brain Aneurysm, Memory Loss And Epilepsy?

Ben Sasse, a Former Republican Senator, has been diagnosed with stage four advanced pancreatic cancer. It was on December 23, 2025, that he took to his X (formerly Twitter) handle to reveal details about his metastasized, stage 4 pancreatic cancer, and stated that 'he is gonna die'. In his strong yet emotional note, Ben revealed that he has less time and is facing hard times with his wife, Melissa. For the unversed, Melissa has been battling many health issues.

Ben Sasse's wife, Melissa, had a brain aneurysm and suffers from Epilepsy

Ben Sasse's wife, Melissa, had battled a brain aneurysm from which she had made a steady recovery. However, in 2024, Melissa got diagnosed with Epilepsy. Ben had stepped aside from his position as the president of the University of Florida to support his wife, Melissa, after her diagnosis. On July 19, 2024, Ben wrote a note to speak about his wife's health condition. He shared that Melissa suffered an aneurysm and a series of strokes in 2007. Back then, the doctors prepared the family for the worst, but – in God's providence, Melissa made an incredible comeback. His note read:

"In the years since – from Nebraska to DC to Florida – she kept our family grounded while I missed too many family dinners, little league games, hugs, and tears. She's the strongest person I know. We've battled some nasty seizures the last couple years, but she's always remained a warrior."

Ben Sasse revealed wife, Melissa, suffered from memory issues

Ben Sasse further mentioned in his note on X that his wife, Melissa, struggled with a new batch of memory issues. The times have been tough on the family, but they faced it together. Ben mentioned making some hard decisions after seeing the condition of his wife. Ben also spoke about his children and feeling blessed to have served as President of the University of Florida. He also spoke about the University, needing a new President. This was because Melissa required his attention, and Ben knew his responsibility back home towards his kids. Ben's hard-hitting note read:

"After extensive prayer and lots of family tears, I today asked UF Chair Mori Hosseini and our Board of Trustees to initiate a search for a new president of the university. I need to step back for a time and focus more on the needs of my family while we rebuild more stable household systems. I’m going to remain involved in serving our UF students — past, present, and future — but I need to walk arm-in-arm with my dearest friend more hours of every week. It's great to be a Florida Gator! … It’s even greater to be a husband and a dad."

Ben, who became a senator twice, departed from his position as President at the University of Florida. Ben dedicated his time to his wife, Melissa, after her Epilepsy diagnosis. For the unversed, Ben's earlier roles included serving as a professor at the University of Texas. He was also the President of Midland University and also an assistant secretary at the Department of Health and Human Services.

Who is Ben Sasse's wife, Melissa?

Ben Sasse's wife, Melissa, comes from a military background, and she grew up in Birmingham, Alabama. She has completed her graduation from the University of Alabama and George Mason University. Melissa had previously worked as a guidance counsellor and a school teacher.

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Ben Sasse to spend Christmas 2025 with his wife, Melissa, amid his cancer diagnosis

When Ben shared the news with his followers about being diagnosed with stage 4 pancreatic cancer, he revealed his Christmas plans. The former Senator mentioned that the family now faces the reality of treatments, but importantly, they will be celebrating Christmas. Ben also shared that since 2024, he and his family have temporarily withdrawn from public life. Speaking of growing close to Melissa, Ben penned:

"Melissa and I have grown even closer — and that on top of three decades of the best friend a man could ever have. Seven months ago, Corrie was commissioned into the Air Force and she’s off at instrument and multi-engine rounds of flight school. Last week, Alex kicked butt graduating from college a semester early even while teaching gen chem, organic, and physics (she’s a freak). This summer, 14-year-old Breck started learning to drive."

What are your views on the health condition of Ben Sasse's wife, Melissa?

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